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New evidence hints at the role of gut microbiota in autistic spectrum disorder
submitted 1 year ago by Drewski from sciencedirect.com
[–]IkeConn 3 insightful - 2 fun3 insightful - 1 fun4 insightful - 1 fun4 insightful - 2 fun - 1 year ago (2 children)
Yea but it's not glamorous doctoring to do shit transplants.
[–][deleted] 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 1 fun3 insightful - 2 fun - 1 year ago (0 children)
Shit, anyone can do that at home.
[–]jet199 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 1 fun3 insightful - 2 fun - 1 year ago (0 children)
Also fecal transplants only last long term in a tiny minority of cases.
The real work is changing diet and lifestyle, which is really unglamorous.
[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 0 fun3 insightful - 1 fun - 1 year ago* (0 children)
I know they are finding imbalances in the gut mircrobiome are associated with a variety of condition. I thought the study design was a bit curious though.
"In this study, fecal microbiota transplant (FMT) via gavage from autistic children donors to mice, led to the colonization of ASD-like microbiota and autistic behaviors compared to the offspring of pregnant females exposed to valproic acid (VPA)."
I don't doubt that they were able to get mice to exhibit autism by altering the microbiome, I've seen them do similar things with other conditions, but one would think the controls would just be healthy mice that simply hadn't been given FMT, yet for some reason they were exposed to valproic acid, brand name Depakote, which is used as a mood stabilizer and anti-seizure medication. This seems like a very strange control group to me, although there may be a good reason for this. I tried checking Sci-Hub for this one to see behind the paywall, but they don't seem to have it.
[–]send_nasty_stuff 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 0 fun3 insightful - 1 fun - 1 year ago (1 child)
This is really fascinating. Thanks for sharing. I wonder how they evaluate what an 'autistic' mouse is vs a regular mouse.
[–][deleted] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 0 fun2 insightful - 1 fun - 1 year ago (0 children)
The autistic mouse thinks he's a girl.
[–]jet199 1 insightful - 2 fun1 insightful - 1 fun2 insightful - 1 fun2 insightful - 2 fun - 1 year ago (0 children)
What came first, the incel or the tendies?
[–]IkeConn 3 insightful - 2 fun3 insightful - 1 fun4 insightful - 1 fun4 insightful - 2 fun - (2 children)
[–][deleted] 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 1 fun3 insightful - 2 fun - (0 children)
[–]jet199 2 insightful - 2 fun2 insightful - 1 fun3 insightful - 1 fun3 insightful - 2 fun - (0 children)
[–][deleted] 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 0 fun3 insightful - 1 fun - (0 children)
[–]send_nasty_stuff 2 insightful - 1 fun2 insightful - 0 fun3 insightful - 0 fun3 insightful - 1 fun - (1 child)
[–][deleted] 1 insightful - 1 fun1 insightful - 0 fun2 insightful - 0 fun2 insightful - 1 fun - (0 children)
[–]jet199 1 insightful - 2 fun1 insightful - 1 fun2 insightful - 1 fun2 insightful - 2 fun - (0 children)